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Module 05 of 12  ·  Hello Pharma AI Upskilling Program

Advanced Prompt Engineering Techniques

Move from user-level to power-user.

📋 Official Content ⏱️ ~25 min read ✏️ Exercise included
📚 5 sections
🏢 Hello Pharma
🎯 6 objectives
⚕️

Hello Pharma AI Upskilling Program

This module is part of Hello Pharma's internal AI capability-building programme, designed to help every team member work with AI professionally and responsibly.

Official Content

🎯 Learning Objectives

  • Write meta-prompts that generate other prompts
  • Build self-evaluation and scoring frameworks
  • Orchestrate multi-step reasoning across complex problems
  • Design prompt chains for end-to-end workflows
  • Implement error detection and self-correction
  • Manage context and memory across long tasks

1. Meta-Prompts — Prompts That Write Prompts

You are an expert prompt engineer. Generate a high-quality prompt for this task: "A regulatory manager needs to explain data integrity requirements to a new IT team in simple, non-technical language." Include: Role · Audience definition · Tone · Format · Length constraints Return only the prompt. No explanation.

When to Use Meta-Prompts

  • Teaching prompt engineering to colleagues
  • Creating templates for repeated use cases
  • Generating first-draft prompts for unfamiliar domains
  • Building shared prompt libraries for teams

2. Self-Evaluation & Scoring Prompts

Evaluate your previous response against: 1. Clarity (1–5): Is every sentence immediately understandable? 2. Completeness (1–5): Are there obvious gaps? 3. Accuracy risk (1–5): Are any claims likely to be wrong? 4. Usability (1–5): Can this be used without editing? Score each with a one-line justification. Then identify the single biggest improvement to make.

3. Prompt Chaining for Complex Workflows

Prompt 1 — Research: Summarise key regulatory requirements for data integrity in pharmaceutical manufacturing. Bullet points only. Prompt 2 — Gap Analysis (uses P1 output): Based on the requirements above, identify the top 5 compliance gaps most common in small-to-medium pharma companies. Prompt 3 — Communication (uses P2 output): Convert the gap analysis into a plain-language memo for a plant director. Maximum 200 words.

Benefits of Chaining

  • Each step can be optimised independently
  • Easier to debug — you can see where quality breaks down
  • Outputs can be reviewed and corrected between steps
  • Reusable chains become automated workflows

4. Context Compression & Memory Design

  • Summarise first — "Summarise this 10-page report in 300 words, preserving all key decisions. Then analyse..."
  • Chunking — Process long documents in sections, then synthesise
  • State passing — "Given these decisions made so far: [list], now decide..."
⚠️ Context Decay

In long conversations, models "forget" early instructions. Re-state key constraints at the end of long prompts, not just the beginning. Or split into fresh prompts with state re-provided each time.

5. Error Detection & Self-Correction

After generating your response: 1. Re-read each claim. Flag any that could be factually wrong. 2. Check that output matches the requested format exactly. 3. Verify that no instruction was missed. 4. If you find any issue, correct it before presenting the final output. Format: [SELF-CHECK PASSED / CORRECTIONS MADE: describe what changed] [Final Output]

✏️ Module 05 Exercise

Design a 3-step prompt chain for a task in your role: (1) research/gather, (2) analyse/interpret, (3) communicate/deliver. Run all three steps. Add a self-evaluation prompt at step 2 and observe the effect on step 3.

🔑 Key Takeaways

  • Meta-prompts multiply your prompt engineering capacity across teams
  • Self-evaluation prompts surface quality issues that manual review misses
  • Prompt chaining handles complexity better than single mega-prompts
  • Context compression is essential for long documents
  • Self-correction prompts add a built-in quality gate before delivery
  • Reusable chains become the building blocks of AI-powered workflows