Engineering Clean-Label, High-Performance Encapsulation for Sensitive Actives
Pullulan capsules, made from naturally fermented polysaccharides, have gained traction as a clean-label alternative for encapsulating dietary supplements and pharmaceuticals. Their superior oxygen barrier properties, transparency, and plant-based origin make them ideal for both consumer appeal and technical performance.
Technical Properties Supporting cGMP Applications
- High oxygen barrier improves stability of oxidation-sensitive actives
- Transparent and tasteless for better consumer compliance
- Suitable for moisture-sensitive and volatile compounds
- Compliant with vegan, halal, kosher, and non-GMO labeling
Manufacturing and Regulatory Fit
- Manufactured under GMP using water-soluble fermentation derivatives
- Validated per USP/EP standards for disintegration and dissolution
- Free from starch, gluten, gelatin, and animal derivatives
- No chemical modification or crosslinking agents
Benefits in Pharmaceutical and Nutraceutical Use
- Natural polymer allows for minimal impact on active ingredients
- Pre-qualified lots support faster QA and release cycles
- Compatible with standard encapsulation equipment
- Low reactivity enhances formulation flexibility
Use Cases
- Plant-based supplements with antioxidant, herbal, or enzyme actives
- APIs requiring high oxygen/moisture barrier
- Products targeting label-sensitive consumer segments
Pullulan capsules enable manufacturers to align regulatory compliance with evolving market trends, offering a bridge between clean-label demands and cGMP-compliant pharmaceutical operations.
